Update (October 2016): The information in this blog post is now outdated. Blocking of .NET 4.6.1 is not needed anymore, as long as relevant updates are installed. Please see this article for more information as well as Exchange Supportability Matrix for versions of .NET that Exchange Server supports.We wanted to post a quick note to call out that since yesterday, the .NET Framework 4.6.1 has been made a recommended update on WU (Windows Update). As we have already stated in the Exchange Supportability Matrix, at this time, this version of .NET framework is not supported by Exchange. In fact, we know of some issues if it is installed. We are working with the .NET team to ensure that Exchange customers have a smooth transition to .NET Framework 4.6.1, but in the meantime, delay this particular .NET update on your Exchange servers (information on how this can be accomplished can be found in the KB article 3133990, How to temporarily block the installation of the .NET Framework 4.6.1).
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