With viruses spreading quick out there today, we had several cases where Exchange transaction logs got either deleted, quarantined or "cured" by file-level anti-virus software that is running on Exchange servers... the result is a bad thing... stores down, transaction logs missing. In some cases the only thing you can do is go back to the last backup if one that is good is available. Otherwise - you are looking at possible repair (= data loss) + Isinteg (maybe 2-3 times) + mandatory offline defrag = a lot of time that is lost :(
Please, do not let Exchange directories be scanned by file-level AV. Not "on-demand" one, not the memory resident one. Have Exchange directories excluded, the M: drive excluded, and actually - exclude specifically .log, .edb and .stm files too just to be extra careful. To be more specific, excluding the following on Exchange server is a GREAT idea:
More appropriate reading:
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