Continuity-of-care, clinically governed AI, and building on Microsoft Azure

In this installment of our Partner Spotlight series, we’re highlighting a partner building secure, scalable solutions on Microsoft Azure and delivering transactable offers on Microsoft Marketplace. I connected with Darren Booker, Founder and CEO of Tali Health, to learn how their clinically governed AI platform helps extend care beyond the clinic while keeping providers in control. By building AI-powered patient engagement on the Microsoft Cloud, Tali is helping care teams deliver more consistent guidance between visits while scaling support without adding burden to clinicians.

About Darren

Darren Booker is the Founder and CEO of Tali Health, a continuity-of-care platform that uses clinically governed AI to extend clinician-guided care beyond the clinic.

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[JR] Tell us about Tali Health—what inspired its founding, and what services do you offer?

[DB] Tali Health is a continuity-of-care platform that uses clinically governed AI to extend clinician-guided care beyond the walls of the clinic. Clinical governance is key—it helps us deliver on-demand guidance and support for patients while keeping providers firmly in control of care.

Healthcare teams invest significant time and expertise developing personalized treatment plans, yet most patient care happens after the visit—at home, between appointments. That’s where confusion, nonadherence, and avoidable complications often occur.

We built Tali to close that gap. Our platform delivers multilingual, care-plan-aligned guidance between visits—helping patients follow provider instructions, understand prescribed medications, and know when symptoms are expected versus when they require attention. Tali also analyzes patient questions and remote monitoring signals—such as blood pressure or glucose levels—and triages them based on thresholds set by the care team.

The result is improved adherence and patient confidence while reducing repetitive outreach and monitoring work for clinical staff.

[JR] Who is your solution designed for, and what problems does it help solve?

[DB] Tali is designed for healthcare organizations and chronic care management vendors that support large volumes of patients who need ongoing engagement outside the clinic—particularly teams delivering chronic care management, remote patient monitoring, and post-procedure follow-up.

The platform acts as an automated, on-demand extension of the care team. Importantly, Tali never diagnoses or makes clinical decisions; it supports clinical teams between visits. Tali is designed to fit into existing provider workflows, including Epic and other EHR-connected environments, so organizations can extend post-visit support without adding disconnected tools.

Patients receive 24/7 support through the Tali app in their preferred language. The system reinforces assigned care plans, answers common questions on demand, and surfaces clinically relevant changes in symptoms or remote monitoring data for care team review.

For example, if a patient reports worsening symptoms or submits monitoring data that crosses a clinician-defined threshold, Tali flags the signal and routes it to the appropriate care team member for follow-up. Meanwhile, routine questions—such as medication timing or post-procedure expectations—are handled automatically through AI-guided responses aligned with the patient’s care plan.

This approach improves adherence and engagement while helping care coordinators focus on meaningful clinical interventions rather than repetitive administrative outreach. By combining clinically governed AI-driven triage with clinician-configured protocols, Tali helps healthcare organizations scale high-touch care models without proportionally increasing staffing requirements.

[JR] Your solution is built on Microsoft Azure. How does Microsoft technology support what you’re building?

[DB] Healthcare data requires a high bar for security and reliability, so we built Tali natively on Microsoft Azure with a HIPAA- and GDPR-aligned architecture. Azure provides the foundation for secure data handling, scalable infrastructure, and regional data residency—capabilities needed to support healthcare providers across multiple markets, including the United States and the Gulf region.

For healthcare organizations evaluating new technologies, trust is essential. Azure helps us deliver AI-powered patient engagement while meeting the compliance, security, and reliability standards required to handle protected health information. 

[JR] What motivated you to publish a transactable offer on Microsoft Marketplace?

[DB] Healthcare organizations are increasingly standardizing procurement through trusted cloud marketplaces, and we recognized early that Microsoft Marketplace would be an important channel for reaching the end users Tali was designed to support—including enterprise healthcare buyers. Publishing on Microsoft Marketplace helps healthcare organizations already operating in the Microsoft ecosystem discover, evaluate, and deploy Tali more easily while aligning purchases with their existing Azure cloud commitments. Because Tali is built on Azure, Microsoft Marketplace also creates a seamless procurement path for customers who want infrastructure, security, and compliance alignment from day one. 

Another key motivation was the opportunity to participate in Microsoft’s selling-with-Microsoft motion. Healthcare providers already working with Microsoft sellers can discover Tali as a complementary solution that extends the value of Azure infrastructure into patient engagement and remote care workflows. For us, Microsoft Marketplace is not just a listing—it’s a strategic go-to-market channel that helps align technology, procurement, and sales motions to accelerate adoption while maintaining the security and compliance expectations required in healthcare.

[JR] Did Microsoft tools like App Advisor or Marketplace Rewards play a role in your journey?

[DB] Absolutely. App Advisor, Marketplace Rewards, and ISV Success all played an important role in our journey. Beyond technical guidance, these all helped us think strategically about how to scale on Microsoft Marketplace—from optimizing our offer structure to building a clean pipeline and aligning with selling with Microsoft and marketplace growth initiatives. For early-stage companies especially, these opportunities can significantly accelerate both publishing and commercialization on the platform.

[JR] AI is a major focus across Microsoft and Marketplace. How are you integrating AI into your solution?

[DB] Tali is unique in its use of clinically governed AI, meaning its response logic is tied directly to the patient’s assigned care plans and medical history. For patients, this means they receive timely, targeted, and easy-to-understand guidance after a visit—whether they’re asking about medications, recovery expectations, or changes in symptoms. Our AI delivers responses aligned with the patient’s care plan while maintaining a fifth-grade reading level designed for broad accessibility.

On the provider side, AI helps identify signals that require clinical attention. Instead of care teams manually reviewing every incoming message or data point, Tali highlights situations where clinician intervention may be needed based on thresholds defined by the practice.

Looking ahead, we see AI continuing to enhance the ability of healthcare organizations to scale high-quality patient engagement—supporting more proactive care models while allowing clinicians to focus their time on the patients who need them most.

[JR] Security and compliance are critical in healthcare. How did you approach building Tali securely?

[DB] As we expanded Tali’s AI capabilities, security and compliance stayed foundational from the earliest stages of development. Because our platform works with protected health information, we designed our architecture on Microsoft Azure to align with the stringent security expectations of healthcare organizations.

Azure provides the infrastructure capabilities needed to support encrypted data storage, secure identity management, and controlled access to sensitive information. These capabilities allow us to implement HIPAA- and GDPR-aligned safeguards while also supporting regional data residency requirements for markets such as the United States and the Gulf region.

We also follow a principle of minimizing unnecessary exposure to sensitive data wherever possible, with access-controlled systems designed to ensure that only authorized users and components interact with protected health information. 

Our goal is to help organizations adopt AI-driven patient engagement while maintaining the security, reliability, and compliance standards their patients expect.

[JR] What lessons would you share with other partners considering Microsoft Marketplace?

[DB] One of the most important lessons is to view Microsoft Marketplace not simply as a listing channel, but as part of a broader go-to-market strategy. Healthcare organizations increasingly prefer solutions that integrate naturally with the technology ecosystems they already trust. By aligning with Azure and Microsoft Marketplace, partners can reduce friction for buyers who want procurement, infrastructure, and security models that work together seamlessly. Another takeaway is to design your solution architecture with enterprise requirements in mind from the beginning. In healthcare, compliance, security, and scalability can’t be afterthoughts—they’re core to adoption. Finally, Microsoft Marketplace can open doors to collaboration with Microsoft sellers and ecosystem partners who are already working closely with enterprise customers. When partners align real customer needs with the strengths of the Microsoft platform, Marketplace becomes far more than a distribution channel—it becomes a catalyst for adoption and impact.

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Closing reflection Tali Health shows how clinically governed AI, built on Microsoft Azure and delivered through Microsoft Marketplace, can help care teams extend support beyond the clinic while maintaining trust, security, and clinical control.